In HONOR of the Healthcare Providers at Jefferson Comprehensive Health Center (Physicians, Nurse Practitioners, Dentists, Nurses, Lab Technician, CNA's, X-Ray Technician, Dental Assistant) and ALL other STAFF.  We THANK YOU for being on the frontline and making a difference.


Welcome to Jefferson Comprehensive Health Center where 


"The Care You Deserve, The Convenience You Need"

Providers at Jefferson Comprehensive Health are ready to meet all of your family general primary care needs, from sniffles to school physicals and beyond. And we offer hours, locations and services that make us more convenient than the ordinary doctor's office.

Jefferson Comprehensive Health Center (JCHC) strives to provide enhanced access and continuity of care. JCHC has the distinction of being recognized as a National Committee for Quality Assurance (NCQA) Patient-Centered


 Medical Home (PCMH).  Patient Centered Medical Home Recognition is an innovative program for improving the quality of primary care. View the following link for more information: 

Jefferson Comprehensive Health Center is an FTCA Deemed Community Health Center. We are a Health Center Program grantee under 42 U.S.C. 254b, and a Deemed Public Health Services employee under 42 U.S.C. 233 (g)-(n).

This health center receives HHS funding and has Federal PHS deemed status with respect to certain health or health-related claims, including medical malpractice claims, for itself and its covered individuals.


  • Family Practice
  • Internal Medicine
  • GYN
  • WIC (Women, Infants & Children)
  • Preventative Dental Care
  • Lab
  • X-Ray
  • Pharmaceutical Vouchers
  • Patient Assistant Program (Medication Applications)
  • Transportation

Jefferson Comprehensive is committed to giving you the most effective primary medical care at the times and places that are most convenient to you. Jefferson Comprehensive has cared for families in Jefferson and Adams counties and surrounding areas for over 40 years

Payor Mix

Private Insurance, Medicare, Medicaid and SCHIP accepted

Payment Options:

  • Visa
  • MasterCard
  • Cash/Check
  • Discover

We offer sliding fee discounts based on family size and income as well as assistance with the cost of prescription medications.

To make an appointment, please call (Fayette) 601-786-3475, (Natchez)601-442-4863, or just simply Walk Right In. 


Services will be provided to all patients regardless of their ability to pay and offers sliding fee discounts based on family size and income. Additional charges will apply for Labs, EKGs, and X-Rays at a discounted rate. 


Visit us at our Fayette or Natchez Locations!!

Fayette Site                                       Jefferson Co. High School Campus            Jefferson Co. Middle School
405 Main Street                                  2277 Main Street                                             Hwy 33 South
Fayette, MS 39069                             Fayette, MS 39069                                          Fayette, MS 39069
601.786.3475                                     601.786.9645                                                  601.786.8206
Natchez Site                                      Gilmer-McLaurin Elem. School                   Morgantown Middle School
145 Homochitto St                              170 Sgt Prentiss Drive                                  101 Cottage Home Dr
Natchez, MS 39120                             Natchez, MS 39120                                      Natchez, MS 39120
601.442.4863                                      601.446.5646                                                601.445.4806
 JCHC-Thompson Head Start         Joseph L. Frazier Elementary School-Based Clinic
 1038 North Union Street                   1445 George F. West Sr. Blvd.
  Natchez, MS 39120                          Natchez, MS 39120
  601.442.3956                                    601.445.2885

 For Clinical Advice After-Hours, please call (601) 786-3475




JCHC's approach to meeting local needs is to become an integral part of the community and strive to be involved in activities such as public housing projects, schools, churchs, community centers and on-site services.

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